Non-Invasive Positive Pressure Ventilation (NIPPV)

  • Mechanism: Delivers a constant, steady pressure throughout the entire respiratory cycle, helping to keep the airways open
  • Indications: Often used for patients with obstructive sleep apnea, congestive heart failure, or other conditions where airway collapse is a concern
  • Settings: The primary setting is the pressure level (measured in cm H₂O), which is typically adjusted to the patient’s needs
  • Mechanism: Provides two levels of pressure: a higher pressure during inspiration (IPAP) and a lower pressure during expiration (EPAP)
  • Indications: Suitable for patients with conditions such as COPD exacerbations, acute pulmonary edema, and hypercapnic respiratory failure, where both ventilation and oxygenation need support
  • Settings:
    • IPAP (Inspiratory Positive Airway Pressure): Controls the level of pressure during inhalation, aiding in overcoming airway resistance and improving ventilation
    • EPAP (Expiratory Positive Airway Pressure): Maintains airway patency during exhalation, similar to PEEP
    • FiO₂ (Fraction of Inspired Oxygen): Adjusted to meet oxygenation requirements
  • IPAP and EPAP: Expressed as IPAP/EPAP (e.g., 15/5 cm H₂O), indicating the pressures during inspiration and expiration, respectively
  • FiO₂: Specify the percentage of oxygen being delivered
  • Mode: Indicate if the machine is set to spontaneous (S), timed (T), or spontaneous/timed (S/T) mode
  • High IPAP: Typically used in cases requiring increased ventilatory support, such as in hypercapnic respiratory failure
  • Low EPAP: A lower EPAP can be beneficial for patients with hypoxemia without significant hypercapnia
  • FiO₂ Adjustments: Aim for the lowest FiO₂ that maintains adequate oxygenation to reduce the risk of oxygen toxicity